Biohacker Bryan Johnson is not holding back when it comes to his thoughts on AG1, a supplement powder that has gained massive popularity online thanks to influencers.
Johnson, who is known for his rigorous health regimen and claims to be biologically over a decade younger than his 48 years, called AG1 “an influencer heist” and urged people to stop spending money on it.
He focused on the lack of clinical evidence behind the supplement, which claims to support gut health, boost energy, improve immunity, and fill nutrient gaps.
Johnson, who reportedly takes over 100 supplements daily, warned followers that AG1 might not live up to the hype.
What the Clinical Trial Really Showed
Johnson pointed to a resurfaced 2024 clinical trial published in the Journal of the International Society of Sports Nutrition.
The study involved 30 healthy adults—15 men and 15 women aged 18 to 50—half of whom took AG1 for four weeks, while the other half used a placebo.
Researchers collected stool samples and asked participants to complete questionnaires about their digestive health.
The results indicated minor improvements in the gut microbiome—the community of bacteria that supports digestion, immunity, and metabolism—but these changes were not statistically significant compared to the placebo.
Essentially, while no harm was reported, the study didn’t provide strong evidence that AG1 delivers meaningful benefits.
Cheaper Alternatives Johnson Recommends
Instead of spending nearly $80 per month on AG1, Johnson suggested two cheaper options: chicory inulin and resistant starch.
Both are believed to support gut health, regulate blood sugar, and maintain weight.
While research shows potential associations rather than proven effects, these supplements are far more affordable.
- Chicory inulin is a natural soluble fiber found in foods like asparagus, bananas, garlic, artichokes, leeks, and onions. Studies indicate it may help improve bowel regularity and blood sugar control. For example, a four-week study in adults with constipation found that 12 grams per day helped participants have softer stools and more frequent bowel movements.
- Resistant starch resists digestion in the small intestine and ferments in the large intestine, feeding healthy bacteria and promoting fullness. A 2022 review suggested it may improve insulin sensitivity and appetite control, though it remains less studied than other dietary components.
Both supplements are significantly cheaper than AG1.
A month’s supply of AG1 costs $79 with a subscription, compared to $13–$25 for chicory inulin and $20–$40 for resistant starch.
Johnson’s Social Media Take
On X, Johnson wrote: “I’d cancel your AG1 subscription.
They just completed a clinical trial and the results show no clinical benefit.
This has been obvious for years. AG1 has no real product substance and is fundamentally an influencer heist.
AG1 is not worth $79 [per month].”
AG1 responded promptly, defending its product and research program: “This year-old study doesn’t say what you’re claiming.
It showed improved nutrient status and digestive quality of life, consistent with multiple randomized, placebo-controlled AG1 trials. Data > narratives.”
The brand added that their research demonstrates positive impacts on digestion, immunity, and energy, emphasizing transparency and standing by their studies.
The Study’s Details
The 2024 clinical trial included stool and blood sample analyses, alongside detailed digestive health questionnaires.
It found slight increases in beneficial probiotic species such as Lactobacillus acidophilus, Bifidobacterium bifidum, Lactococcus lactis, and Acetatifactor sp.
While daily consumption appeared safe, the study concluded that the results were not statistically significant and suggested that further research, especially in people with gastrointestinal issues, might reveal stronger benefits.
AG1 continues to reference this and previous studies on its website to support claims that the supplement improves gut health, immunity, and energy levels.
Potential Side Effects of Alternatives
While chicory inulin and resistant starch are generally safe, higher doses can cause bloating, abdominal discomfort, loose stools, and gas.
Moderation and gradual introduction are recommended for anyone adding these supplements to their routine.
Bottom Line
Johnson’s critique raises an important question about influencer-driven health trends: are the claims real, or are they simply marketing hype?
While AG1 remains popular and supported by some research, biohackers like Johnson encourage people to consider more affordable and potentially effective alternatives, especially when evidence for costly supplements remains limited.
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