After years of being in the spotlight, Rosie O’Donnell is once again getting candid—this time about her health journey, her surprising weight loss, and what life looks like after relocating to Ireland.
The 63-year-old comedian and TV personality recently gave fans a major update through social media, and the transformation has left many stunned.
Sharing Her Transformation on Stage and Online
Taking to Instagram, Rosie unveiled her noticeably slimmer figure as she performed stand-up comedy in Ireland.
Wearing a sunny yellow sweater over a blouse and paired with blue pants, she stood confidently onstage—marking a new chapter in her journey.
Alongside the photo, she wrote, “i cant believe this is me now #mounjaro #weightloss #bodydismorphia.”
Her followers flooded the comments with love and encouragement.
One fan said, “You look great Ro!!! I’m glad you’re feeling better and taking care of your health!” Another asked how much weight she had lost, to which Rosie replied simply, “Dunno.”
How Mounjaro Played a Role
Rosie first revealed she was using Mounjaro in 2023.
It’s a prescription injectable medication that helps regulate blood sugar for adults with type 2 diabetes—but one of its side effects is weight loss, which she has embraced as part of her health overhaul.
In a TikTok clip from earlier this year, Rosie explained, “I am on Mounjaro for my diabetes, and one of the side effects is you lose weight.”
But she also credited everyday changes, like cooking her own meals instead of relying on a chef.
“It’s just me and Clay now,” she said, referring to her nonbinary child.
A Surprising Size Shift
During a trip to Dublin, Rosie walked into a clothing store and found herself fitting into a size large—down from the XL and XXL sizes she was used to.
“I find it shocking. I really do,” she said, still adjusting to the changes in her body.
In another TikTok, Rosie reflected on the start of her weight loss.
After Christmas 2022, she lost 10 pounds and credited it not just to medication, but to cutting out diet sodas and switching to drinking mostly water.
She did admit to enjoying a few celebratory drinks now and then, but said the shift away from sugary drinks was significant.
Fans Join the Conversation
Rosie’s openness has encouraged others to share their journeys too.
One fan proudly commented, “I’ve lost 110 pounds on Mounjaro. My A1C is in check.
Blood sugar normal.” Another chimed in, “Good for you, Rosie!!! Shine ON!”
Still, some raised concerns about accessibility.
A commenter pointed out the high cost of the drug, and Rosie acknowledged that it’s typically only prescribed to people with diabetes. “That’s what I heard,” she said.
“People are doing Ozempic parties here in L.A., but I have diabetes too, so that’s why I’m on it.”
A Look Back at a Life-Changing Health Scare
Rosie’s motivation to take her health seriously stems from a major scare over a decade ago.
At age 50, she suffered a heart attack but didn’t realize what had happened right away.
She recalled helping a stranger in a parking lot and later feeling arm pain—only to learn two days later she had experienced a massive heart attack.
On a podcast, she admitted, “I should’ve died.”
She also criticized how women’s heart attack symptoms are often overlooked, noting how media usually portrays male-centered symptoms.
Building a New Life in Ireland
Beyond her health journey, Rosie has embraced big life changes—like leaving the U.S. in late 2024 after Donald Trump’s re-election win.
She and Clay relocated to Ireland, where she’s now getting back into stand-up comedy.
Her fans can even catch her performing in person, with shows scheduled between May 28 and July 23 at the International Bar in Dublin.
She’s also been documenting her Irish life and health updates through TikTok, keeping fans looped in every step of the way.